Epigenetic abnormalities in cardiac hypertrophy and heart failure
نویسندگان
چکیده
منابع مشابه
Cardiac Hypertrophy and Heart Failure
In cardiac and skeletal muscle, the sarcoplasmic reticulum (SR) plays a central role in the contraction relaxation cycle of the muscle by virtue of its ability to regulate the intracellular free Ca'+ concentration [Ca'+],. Ca'+ release from the SR increases [Ca'+] (10`mol/L), thus inducing contraction, whereas Ca2` uptake by the SR reduces [Ca'+] (=10-7 mol/L), producing muscle relaxation. In c...
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Heart failure presents a number of difficulties. Its very definition has proved taxing, and the clinical diagnosis is frequently incorrect. Patients with objective abnormalities of left ventricular function are not infrequently asymptomatic, hence treatment is often delayed. Even when a firm diagnosis is secured, only a minority of patients receive optimal medical treatment. Of concern is the i...
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ژورنال
عنوان ژورنال: Environmental Health and Preventive Medicine
سال: 2007
ISSN: 1342-078X,1347-4715
DOI: 10.1007/s12199-007-0007-8